MODEL SYSTEMS 02

Specialists
in a shared world.

Each terminalBio system has a distinct job. Together, they create a composable intelligence layer for designing in biology.

01
MOLECULAR
INTERACTIONS

BindFM

A foundation model for molecular recognition—reasoning across proteins, nucleic acids, small molecules, and cofactors to reveal the interactions that make binding work.

QUESTION

What binds, why does it bind, and how can we improve it?

CAPABILITIES

Affinity prediction · interface reasoning · cross-modal molecular representation · candidate ranking

USE IN THE LOOP

Prioritizes molecules to synthesize and assay, then learns directly from measured performance.

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02
GENERATIVE
APTAMERS

XUZU

A generative design system for aptamers that treats sequence, structure, target context, and experimental feedback as one iterative search problem.

QUESTION

Which sequences have the highest likelihood of becoming useful binders?

CAPABILITIES

Constrained sequence generation · structure-aware ranking · diversity selection · wet-lab feedback integration

USE IN THE LOOP

Generates a small, information-rich library—not an unranked flood of sequences.

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03
RNA
INTELLIGENCE

RNJ / RNX

RNA structure intelligence for reading and designing a molecule whose function depends on a moving, contextual geometry—not sequence alone.

QUESTION

How does an RNA sequence fold, behave, and change in the context where it must work?

CAPABILITIES

Secondary-structure reasoning · RNA representation learning · sequence-to-function analysis · therapeutic design support

USE IN THE LOOP

Connects predicted structural behavior to expression, activity, stability, and experimental readouts.

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04
COMPUTE
SUBSTRATE

TB Biocompute

The composable infrastructure beneath the model layer: a consistent way to run, compare, connect, and build biological intelligence systems.

QUESTION

How do specialized models become a reliable, reusable scientific system?

CAPABILITIES

Reproducible evaluation · interoperable data and model interfaces · experiment tracking · agent-ready orchestration

USE IN THE LOOP

Makes every model output traceable, comparable, and available to the next decision.

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